Supplementary Table Risk of Breast Cancer Associated with snps in Non-significant tlr or nfκb pathway Genes



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Supplementary Table 1. Risk of Breast Cancer Associated with SNPs in Non-significant TLR or NFκB Pathway Genes


 

 

 

 

 

Controls

 

Cases

 

 

 

 
















(n = 807)




(n = 845)













 

 

 

Function

Maj / Min Allele

0

1

2

 

0

1

2

OR

95% CI

gene wide P

AZI2 (chr 3: 28339090-28365579)


































0.62




rs7613767




flanking 3' UTR

G / A

408

344

47




438

345

56

0.99

0.85

1.16







rs4393865




intron

G / A

439

304

58




479

309

51

0.91

0.78

1.07







rs12054402

*

intron

A / G

696

103

2




734

101

5

0.96

0.72

1.28







rs7649498




flanking 5' UTR

C / A

239

419

143




256

436

148

0.98

0.85

1.13




IFIH1 (chr 2: 162831835-162883285)


































0.69




rs1990760




coding (A946T)

A / G

310

365

125




315

388

136

1.04

0.90

1.19







rs3747517




coding (H843R)

G / A

427

321

53




444

325

69

1.05

0.90

1.22







rs10930046




coding (H460R)

A / G

780

21

0




821

17

0

0.76

0.40

1.46







rs17715343




intron

C / G

667

125

9




712

123

5

0.88

0.69

1.12




IKBKE (chr 1: 204710419-204736845)


































0.12




rs6657352

*

flanking 5' UTR

G / A

701

97

2




724

110

4

1.12

0.84

1.49







rs1930437




intron

C / A

217

399

185




223

421

195

1.01

0.88

1.16







rs34253940




intron

A / C

308

375

118




331

399

110

0.95

0.82

1.09







rs1539243




coding (I67I)

G / A

566

219

16




577

240

23

1.11

0.92

1.33







rs2297546




intron

C / G

323

363

115




286

414

140

1.20

1.04

1.38







rs1953090




intron

A / C

431

316

54




465

323

52

0.95

0.81

1.11







rs11117909




intron

G / A

622

167

11




626

203

11

1.16

0.94

1.43







rs2297545




coding (T239T)

G / A

482

279

39




493

295

50

1.08

0.91

1.27







rs12724769




intron

A / G

192

411

197




236

403

196

0.90

0.78

1.03







rs41299005




intron

G / A

643

147

9




714

121

5

0.73

0.58

0.93







rs11118087




intron

G / A

421

315

65




436

331

73

1.03

0.89

1.20







rs11118092




intron

G / A

317

379

105




354

366

120

0.97

0.84

1.12







rs11118132




intron

G / C

349

344

108




324

396

120

1.13

0.98

1.30







rs12728136




intron

G / A

588

198

15




628

193

19

0.96

0.79

1.17







rs41299852

*

intron

A / G

764

37

0




801

38

1

1.01

0.63

1.59







rs17434047

*

3' UTR

G / A

751

50

0




779

60

1

1.18

0.80

1.73







rs2336940




intron

G / C

572

212

17




613

199

28

0.99

0.82

1.19






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